I'll offer a theory here that has little to no academic basis, but certainly seems true from my limited experiences. I've walked with Cape Buffalo in three countries, expressly hunting them in just one (Zimbabwe). They are not all the same animal, and how they've lived appears to make a huge difference in their attitude. The same applies for Bison here in Canada, a Wood Bison that's been wild for millenia pressured by wolves who's never seen a human acts shockingly different than a southern plains Bison. My scariest moment with wildlife is a tie between a bear and a Wood Bison not Cape Buffalo or Lions, but those are different stories.
My wife and I photographed essentially tame Cape Buffalo in South Africa in a hunting area, some replete with ear tags, and while we were cautious I'd have no qualms approaching to fifty yards and even a bit inside with only a camera on them if the picture of a lifetime presented itself. Never would I do that on the Zimbabwe bulls in the jesse. They are an entirely different animal, and act it, even the body language of PHs tells the difference between the two. My friend in Zim mouthed to me a wide eyed and stern "Don't miss." on my bull there as we bumped him in thick bush at loogie range. The South African bulls would chew and stare at you in the truck from that range.
In short, in South Africa, on most operations where the entire predator chain is not there and intact and the demeanours of the bulls rather soft, I'd use my No.1 with no qualms. In thick jesse (thorn bush) in Zimbabwe? Hell no- unless you're paying for it, for free I'd use a pointy stick on a hooped stick and string, and people happily pay to do that. But personally, from my experiences in Zim, if chasing the nasty bulls in thick stuff you'd really prefer you'd brought your bolt or double once in there. I shot my bull several times despite it being in our faces closer than I'll likely ever be to another dangerous game animal alive, at the direction of the PH, you "Keep shooting!".
If you ask me, they are almost different species, wild, and semi-domesticated. They even look different, with the Zim bulls carrying dark, coarse, extremely long hair and a more muscular body, with less horn of course generally than top South African stock.