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4506, P220 and Glock 21 would be my first recommendations. The 21 is an incredibly robust gun. Designed for the 10mm then adapted to .45 which is usually the opposite case.
-- GLOCK 21SF -- Find an SF if you can - so comfortable and the recoil is very soft - can shoot hundreds of rounds consecutively without any hand/wrist discomfort whatsoever.....enjoy one soon! Easy to find/buy and simple to sell if you need to...!