I put over 90 000 rounds through a Sig P229 in 40 cal and there was very little frame wear.
We retired the gun because the trigger return spring locator hole near the slide catch was starting to wear in an oval pattern and our gunsmith felt it MIGHT fail (it was a duty gun and I would bet my life on it). My 229 after that had 30 000 rounds through it with zero issues except for failures to feed during the break in period that went away after 400 rounds.
As for the slide, it was on slide number 2, firing pin number 4 or 5 and barrel number 3... the barrels developed flat spots around 25 000 and 30 000 rounds. Slide number 2 was required because I broke a firing pin and we could not get the locator pin to come out. Wear on the slide was not excessive and was limited to holster wear.
My current 226 is around 10 00 rounds and looks almost brand new. Frame wear is normal and is limited to only bluing/anodizing wear.
Note, Sigs are wet guns and should be well lubed! Slide rails, frame rails, barrel, trigger bar.
Oh, BTW, I was an adjunct instructor at the Sigarms Academy in 2005, 2006.