Maybe not the usual go-to brands, but there is powder out there. I lucked out and got 10 lbs of very inexpensive powder (when they had it), and could not be happier. Took a bit to work up a loads but that is the fun of reloading!!
It is fun, but the real beauty of reloading is that you can just about always find a recipe for your rifle, with just about any powder that is within the safe parameters listed for your particular rifle/cartridge combo in several different manuals and find a sweet spot that you can depend on, when it's important.
The main reason I went away from factory loads, was that every time there was a lot # change, the characteristics of the cartridge would change and scopes/sights had to be adjusted accordingly.
Often, there would only be one or two boxes of the same lot on the shelf or the rifle just wouldn't settle down well enough to trust that lot. At least with handloading, you can tune a load to the individual rifle.
Example, I have two identical 7.65x53 Mausers. Their chambers are so close I can't see or measure any difference between them. Seating depths are, of course, limited to the length of their mag wells. The leades are well beyond that. Both have excellent bores and both are from the same crate, with serial numbers only one last digit apart. To bad they were bubbaed.
One will shoot a load about 150fps faster with the same components, charge weights, bullet weights, than the other.
The rifle that shoots slower with that load isn't as accurate as the faster barrel.
If I tweak the load with 5 grains of the same powder, to get the same velocity the groups tighten up and there aren't any pressure signs.
If I use the heavier load with the faster barrel, I get flattened to the point of flowing primers and other pressure signs, such as a very distinctive expansion ring. The accuracy goes the way of the willow as well.
Both loads are within the listed safe parameters of the #7 Hornady, had to go back and check, manual.
You just usually can't get that flexibility from factory loads, especially with older firearms that weren't machined on CNC lathes.
I can remember when it wasn't uncommon to go to a yard sale or gun show and find several partial boxes of ammunition.
The sellers had gone through several lots before they found one that their rifles would shoot acceptably.
We don't see that as much today.