Depends on the ammo... if running match ammo with oily lube, you can swab out the action every couple of hundred rds. A mud will form so it looks bad but easy to clean, at least to get more rds downrange. Q tips for an easy clean.
it really matters to keep the chamber and throat clean. The rest of the bore is not as important but a chamber can foul up enough to cause function issues. If you are just running a sporter chamber, it will be more tolerant of fouling vs a match/tighter chamber.
I would take it apart every 500rds and do a more detailed clean... but I am looking for 100% reliability in competition.
Jerry