Is up to you and what you do with the rifles? - I started like many - a rimfire 22 Long Rifle, a bolt action 308 Win and a 12 gauge Pump action.  Then got a 22-250 for me.  Then got a 243 Win for my wife to hunt deer.  Then got a 338 Win Mag for me to hunt elk.  And it kept going from that.  I was just texting with an acquaintance - same issue - if looking to "thin the herd", what is preferable to end up with ...  For me, I would keep the 30-06 and sell off the other two - but you are not me, and we likely have different wants/needs.