I am talking about factory loads as I know very little about loading up the 45 colt. To me it's dated technology and there are better performers out there, like the 44 Mag.
Before you make your mind up about the .45 Colt do some research, you'll be pleasantly surprised. There's some excellent reading on the .44 & .45 in these articles regardless of your opinion.
http://www.customsixguns.com/writings.htm
Whatever the .44 Magnum will do, the .45 Colt will do with roughly 1/2 the barrel length, pressures being nearly identical. From the limited pressure testing we have done, we have found that whatever the .44 Magnum will do, the .45 Colt will duplicate with about 5,000 psi less pressure. This is with standard bullet weights. As the slugs get heavier the gap widens.



















































