At one time there was an entire class of smokeless and semi-smokeless powders which were safe in Black Powder guns. These were the old BULK powders. They could be loaded BULK FOR BULK with Black and would give similar performance internally as well as externally.
There was, however, a serious difference: the Bulk Powder charge WEIGHED a lot less than the Black charge.
The Bulk powders have all gone the way of the Dodo Bird, but there is ONE old-time powder left which is ALMOST in the same class, but not quite. This is SR-4759. The SR is for "Sporting Rifle"; it is emphatically NOT an IMR (Improved Military Rifle) powder.
Using SR-4759 in RIFLES, you can pretty much duplicate the Black Powder performance by using the SR-4759 at 38 percent of the Black charge BY WEIGHT. It is a very bulky powder but you can NOT load it bulk-for-bulk as the old-time powders were loaded. At 38 percent-of-Black levels, this works out to 29 grains for my .43 Mauser, about 27 grains for a .45-70, 38 grains for a .50-100 and 42 grains for a .50-110 Express. In each case, you have a charge which will duplicate the Black powder performance AND pressures; you will also have pretty near a full case.
SR-4759 works fine in RIFLES (but I still run my Sniders on Black) but it is NOT for shotguns, nor is it for pistols. It would NOT be safe in either gun.
For pistol cartridges, you CAN use LIGHT charges of the faster single-based and double-based powders, but in NO case are these charges anything at all of the order of the original Black charge. A friend is using 6 grains of Unique for his .44-40.... and he is getting much the same performance as if he were using the full FORTY grains of Black.
There is a HUGE difference between modern smokeless powders and the original Black powders. The ONLY near-exception is the very last of the old-time powders: SR-4759.... and you have to know how to use it and you have to be CAREFUL with the stuff.
There is NO smokeless powder which you can load bulk-for-bulk with Black, using your little dippers or powder-horn measures. The very last of these powders went to the knacker's yard many years ago. What we are left with is their COUSIN, so to speak, an ALMOST-but-not-quite-Bulk powder: SR-4759 (long may it continue in production!).
HOPE this is clear enough.
DON'T want anyone getting hurt.
PLEASE read carefully.
.