Not bad. I have a Ruger MKII 77 in stainless 350 rem mag set up similar to that, 19" barrel, short action, stock shortened 1". Very handy gun, and stupidly accurate with 200gr factory ammo. Will be playing with some 250gr Speer's this summer to see what they will do.
For a factory jobbie, the 338 would make a bit more sense. As much as I love the 35's, and as potent as the 375 Ruger is, try to find factory ammo for them when you're outside of a major city. At least 338's can be found in most Canuk tire & Wallyworld stores. Bark a bit? No doubt, but that would be more than enough gun to slap 'em silly. And for whatever velocity loss ther would be, don't think your object on the recieving end of that beast will really notice a few fps less. They will definately notice a nice stout 250gr though.