Yes... after the thief made it into your front door, past the locks and or dead bolt, past your security system, all the people in the dwelling, located the safe you have hidden, realized its a Vaultek safe, gets his or her laptop, downloads the software, they will begin to hack into the safe.
Once they realize it may take to long. They can pry it off whatever surface its attached to, jump in their hover craft and make their way to their evil lair on an island in the pacific at the base of a volcano to finish the job.
These days with everything being automated including locks, security systems, bank accounts and even you cars... Hacking is an unfortunate reality.