30/06
61gr D4350SSC 150TTSX RP brass gives 2870 fps whereas the same charge of H4350 in this load gives 3125 fps. There isn't any more room in the case so that's that.
6.5 RM
54gr D4350SSC 143 ELDX RP brass gives 3020 fps with slight pressure signs whereas the same velocity is achieved with the same charge weight of RL 22, no pressure.
6mm Rem
45gr D4350SSC 105 RDF WW brass gives 3040 fps whereas the same velocity is achieved with 43 gr H4350.
So my guess that this is significantly slower than the 4350's I have played with. To the point it is out of room in some cases like the 30/06.