Be careful with substituting to achieve ballistics ! Yes you can but, going by a burn rate chart for instance is just the very "first" step in load development, I have been loading and casting since the 70s, I use "gallery loads" (reduced loads) for cost effectiveness and also experimented with "like " burnt rates to test (such as Leverevolution in place of CFE223 and varget for instance) to get maximum fps.
Position sensitive powders, reduced powder capacity, too slow a powder for case volume just to name a few...you can have a bad day if your primer flame jumps your reduced powder charge and burns from both ends or ,too slow a powder in a large case full and the primer only pushes the projectile into the rifling, now you have an obstruction and with a hang fire !you can guess what that would do!
Thank goodness for ballistic experimentation, if we didn't have people willing to test in controlled environment with great documentation and science to back it up, we would likley still playing with black powder! There is tons of good resurch and precautions on line and in loading book's.