I'm sure you know this already, but since we're talking about accuracy, it's worth mentioning that 22lr headspaces off the rim, not the case mouth. Apart from powder charge and bullet weight, really good ammo has a much more consistent rim thickness (similar to the way a benchrest shooter controls the headspace with shoulder bump for pressure and bullet jump consistency.
Lube and carbon do build up in my Aschutz, and after about half a brick, I need to give it a good soak and scrub. I "feel" this in the bolt close as the extractor grabs the rim, but so far haven't noticed one bit of impact to overall accuracy.
Others may have a different experience, but for me, generally speaking, the less I clean my rimfire target rifle, the more consistently it shoots, so I'm not convinced that fouling around the throat and the end of the chamber affects shot-to-shot repeatablity on the paper. In fact, after I give it a good cleaning, it can take a box of ammo before it settles down again.
My 2cents for what they're worth.