that depends on bullet weight more than anything else- lighter bullets shoot lower, - ie your 45 acp can run the whole gambit from from 185 to 230 plus grain- jacket vs cast makes little difference at 45 acp velocities- your factory loads are typically 230 grain round nose- i shoot 200 grain lead swc to just about the same poi, but the 185's cause nothing but grief, either jacket or cast
I hear you on the bullet weight difference, that's why I got 230 grain cast lead, round nose bullets to load up, as I had been shooting 230 jacketed, Winchester ammo from factory and it hits perfectly. It's shocking the difference between them, but as I said I really should get some 230 jacketed bullets to load up and compare to the factory stuff.
The cast bullets do group better than the factory, they just hit low.