I have a Sako 995 in a 30-378!
Pros, well one key factor velocity, and down range energy
Cons, well you just do not need all that horse power.
Cons, can be finiky to load, but once you find it accuracy is good
111.0 grains of powder lots of bark, significant more recoil,
To date I have shot 2 animals with it, one deer and one bear, you can not question it effect, but you need good bullets TSX I would suggest.
If I had to pick between a 300 wm and a 30-378 the 300 wm woudl bring home first prize.
a 300 wby is a good in between and has only 200 fps behind that big brothers case.