Suputin, have you tried H110 or Lil' Gun in a boltgun? With subs, the noise isn't bad at all. I agree with you regarding fast pistol powders. Where the OP is presumably new to the cartridge and possibly subs in general, sticking with published load data is a good idea initially. Wouldn't you think?
I've tried Lil Gun and W296 and they can be fairly quiet at lower velocities but by the time you get up around 1000 fps they get considerably louder. The problem is that my idea of quiet is quite different and for different reason. I also have the sound meter which tells me in no uncertain terms which is quieter and by how much. Going subjectively by ear can easily lead you astray due to how we perceive sound levels.
If we were talking about building subsonics in a larger case with a long barrel then it is safer to go with established data. However there is a lot of valid 300 BLK data that is not published and with the short barrels we use, the chances of getting a round stuck is pretty low. In a way the reloading companies are a bit behind the curve on this. You can see this by looking at the published data, the majority of it is for subsonics, especially where a bullet weight could be used for either.
As long as he isn't loading crazy small amounts of powder (I usually never go below 30% case volume) then he should be OK. It'd be pretty difficult to seriously overpressure a subsonic round. Even a double charge wouldn't come close and for powders like TB that isn't even possible.
Looking up my data I got the following out of my 12" special bolt gun YMMV:
200gr Lapua bullet:
N320 6.3gr (70% load density) 997 fps [123.3 dB]
HS6 7.0gr (50% load density) 981 fps [125.9 dB]
Trailboss 5.7gr (100% load density) 613 fps [116.7 dB]
Blue Dot 7.0gr (60% load density) 965 fps [124.0 dB]
AA#5 7.0gr (45% load density) 978 fps [121.6 dB] note this load tends to throw wild flyers
150gr FMJ-BT:
Trailboss 6.0gr (100% load density) 791 fps [117.8 dB] - I am fairly certain that 6.5gr can be gotten into the case with this bullet which would give a bit more velocity.
The Trailboss loads are ludicrously quiet