I had both the .300 and .340. Loaded for both and if you put a 250 Barnes TSX in the .340 and zero it at 300 yards, you will SMASH anything out to 600 and completely pass through any animal short of the Dangerous Game in Africa (which I have no experiance).
The .300 is a great round, but the .340 will really impress you once you get used to it and the recoil . I have shot elk, moose, bears, deer with the .340 and at one point it was the only hunting round I used.
The .338 caliber really puts the hurt on animals. I also shot the 275 Swift A-Frames in the .340 and THAT is one hell of a great moose load!!!!
As for velocities the .300 ran 180 gr bullets around 3150+ and the .340 pushed 250's to 2900+. Look at the Rl-22 and RL-25 powders, or H1000, Retumbo for both and if you do up you load development properly you will be impressed!!!!
PM if you have anymore questions!!!
later