Sorry I didn't notice earlier. The 338-06 and 225 is ackward combination. The perfect case filling powder is 4 grains slower than 4064/Varget and 2 grains faster than 4350. Higginson 47N would have been perfect,except they were sold out when I started reloading my 338-06. A 24" barrel should top out at 2700,a more realistic goal with 22" barrel would be 2650. Last Saturday 61.0grains of VihtVouri N-550 gave a extreme spread of 7f/s and 2645f/s with my 22" barrel.The soft shelled CCI had half their radius,too.I started at 58 grains,and worked up,which I suggest you do too. 55.0 grains of IMR 4064 gave 2611,but I lost 3/4 of the primer radius.poor group,too.Hope this helps.