... but mostly for grizzly bear....
Compared to what you will spend just on fuel for the hunt, any cost difference for ammo between .338 Win Mag and .300 Win Mag is completely insignificant.
If it was me hunting grizzly I would be carrying nothing smaller than a .338 Win Mag, it is a significant step up from the .300 in terms of power.
Mark
I'm still waiting for my .338s to start killing better than my .300s. I want them to, and have been encourageing and supportive, but I'm still seeing more difference between bullet types than the two cartridges.
Fair enough, but for grizzly I will take a 250gr @ 2700fps over a 180gr @ 3000fps. Maybe that is just me. A 30-06 will work just fine, too, if you always get a perfect shot.
YMMV.
Mark
I split the difference, and went with 225 TSXs at 2800 fps. I was looking for a compromise bullet for griz and goats on the same hunt, though the goat portion never came off. I did have 275 grain A-Frames on my belt that shoot to a 150 POI when the scope is zeroed for the TSXs at 200. One even got used as a finisher when the bear wouldn't quit squirming. There's a very noticeable difference between those two bullets in visual impact signs.
I'd like to crack a couple buffalo with the 275 A-Frames some day, just for couriousity.