Loading Black Powder cartridges has been covered here many times, you determine overall cartridge length, then fill and settle(drop tube or vibrate) the 2fg black in the proper quantity to fill the case to the bottom of the bullet. Some experimenting and weighing are in order and make sure the cast bullet is very soft, pref. 30-1, and lubed with Black Powder lube. There must be no airspace in the loaded round. For the model '76 or repros, light smokeless loads, must be arrived at carefully, these actions are not strong. AA5744 or IMR 4759 loads meant for the Trapdoor may be a baseline, reduce 10% for the 45/60 and increase somewhat for the 45/75.