When A-Zone and I were in Africa this summer, between the two of us we shot in excess of 40 animals with our .270's -- me using 130 grain Hornady Interbonds (the next best thing to Accubonds), and he using 130 grain TSX's.
Everything we shot died, but bullet performance was very different. Only 1 TSX was recovered -- all the others exited. Relatively few of the Interbonds exited on anything over 300 lbs, but they killed everything quite dead. The recovered Interbonds showed that weight retention was quite high (around 90%), but the expanded diameter was enormous -- one bullet recovered from a hartebeest had expanded to 0.7"

yet still weighed 120 grains.
The end result is that bonded bullets seem to have less penetration due to their expanded diameter -- but the flip side of that is that they seem to transfer a hell of a lot of shock to the target.
I had no trouble killing critters in the 600-700 lb. range with the bonded bullets, but would have to say that the Barnes TSX bullets probably get the nod if your rifle shoots them well. A-Zone didn't have to chase his animals very far either -- but in his case there was usually a much better blood trail.
As much as I liked the end result of the bonded bullets, I'm going to switch to the TSX's if I can find a load that yields enough accuracy to keep me happy.