I think 72 grs of H-4831 is as good a load as any for the .300 Winchester with a 190, but most powders from 4350 to Re-25 can produce accurate ammo with good velocity from this cartridge. More critical to accuracy are the idiosyncrasies of VLD bullets. I prefer to have the bullet supported by the rifling to help center it in the bore. For this reason I would opt to seat the bullet hard into the lands, thus giving the bullet a supported position in the chamber. But your ability to do this depends on the length of the bearing surface of your particular bullet, the depth you seat the bullet into the case neck, and the length of your chamber's lead. The 190 gr Burger has a bearing surface of .469." If we seat the bullet so that .200" of the bearing surface is in the neck of the cartridge, that leaves .269" to bridge the space between the case mouth and the rifling. This length should be sufficient unless your rifle has a very long lead for seating heavy bullets without crowding the powder capacity of the cartridge.