I load .45 Colt with 3Fg under a 260 grain LRN (soft cast) in an SAA replica; .45-70 with 55 gr (with filler) 2F under a 405 - 450 grain boolit in my Marlin (surprisingly accurate!); and .45-90 WCF in my 1886 although I haven't dialed in an ideal load on that one yet (bore is not good it'll take some time, which I don't have). I have loaded .32 RF in black as well.
I brought out the .45 Colt a couple of years ago at one of our informal steel matches, in a deeply bermed pit. The first shot I knocked the popper down, after a couple more the smoke was so thick I couldn't see the rest of the poppers and was just guessing, I think I shot 2/5 down. I can only imagine what the old battlefields looked like in the thick of it!
I also note that a full charge of BP in my SAA is brutal on the hands - far worse than light "cowboy" type loads. I use cornmeal filler to load it down and it becomes fun again.
I use a drop tube and (usually) over powder cards on rifle cartridges but for the .45 Colt I just compress with the Boolit and shoot. Works fine. I use a simple lube of roughly 50/50 beeswax and olive oil. I lube the whole gun with olive oil for this which actually works fine with smokeless too (so I don't have to switch all the time). The only thing I do notice is that olive oil alone doesn't protect over the long term, so if you're planning on putting it away for a few months or longer, do oil it with something better.