Ammunition can be of high quality using either system. There was a test done a while back with Berdan primed 6PPC ammunition, and its performance was superb. The thought was that the multiple jets from the twin Berdan flasholes gave better ignition. For practical purposes, either works just fine. I have reloaded a lot of Berdan ammunition, and its no big deal. But if Boxer cases are available in a given calibre, there is little reason to use Berdan primed cases.