Hi,
The Thompson-Center Contender was produced in 45 Long Colt, and was capable of shooting .410 if I recall correctly.
I believe that there was also a choke-tube/muzzle-brake that was supposed to be removed when firing 45LC.
We shot the .410 a lot, including attempts at flying birds & clays to no memorable success. Rattle-snakes at 3m, or less, were toast.
Commercially loaded shot-capsules in pistol calibers were also available, and were fired in rifled pistol barrels. They might, or might not, make a decent pattern on paper at very short distances, but were notably LESS effective on Rattle-snakes at the 3m distance than the TC Contender in .410.
My suggestion is that if you want shotgun performance, use a shotgun.