I'm assuming the frame cracks you mention are at the junction where the dust cover turns into the frame rails, or on the left side frame rail where the slide stop hole has been milled. These are normal, if disturbing, with 1911's run to high pressure and slide speed. Colt began milling out the slide stop hole straight up to eliminate the cracking in that area. As for cracking at the dust cover, all you can do is try to balance your spring weight to the load being used, and possibly use a shock buffer.
I do not recommend trying to shoot .40 in a 10mm barrel, except in a S&W 610. While the extractor may hold the case firmly to the breach face, there is a greater possiblity that the case will have too much play during ignition, and batter the breach face.