i have used both as i am a lefty, but i do feel more natural with a lefthand bolt, i have found by accident that a savage 99 is by far the fastest truck gun for me, i hold it in my left hand by the pistol grip, and put the cartridge in the open action with my right hand close and you are good too go. allthough i dont hunt this way much, its far faster than a bolt, right or left, wade