Well, the 30-06 has accounted for many moose for me.
I usually have used the 165 or 180 Partition in handloads.
I shot about a half dozen with the old-design Winchester 180 gr Silvertip.
Always did the job well.
Last year's Bull fell to a 168 TTSX from my 308 Norma Mag.
As some posters have already said, make sure you put the bullet in the correct place.
Then the hard work begins!
Regards, Eagleye.