Favourite gopher rifle is a Brno ZKW 465 in 22 Hornet topped with a Leupold Vari-X II 2-7. It works on everything inside of 250 yards or so. Occasionally has stretched well beyond that, but that's more for "fun".
The cases are neck-sized ever so slightly - just enough to hold a 40 or 45 grain V-Max - although it works surprisingly well with any soft nosed bullet in that weight range.
Gopher gun #2 is a heavy barreled Tikka in .223 (Tik Tac). That one is just a solid performer.
Hard to top my CZ 452 Lux and the 452 FS, but my latest addition, a few years ago is an Anschutz 1710DKL. My only .22 for many years was a CIL/Anschutz 310.
^sorry prairieguy-only nice rifles/scopes allowed in this thread.lol
What a beauty, done any big-# days with that rig?