HARD!
I'm using the 340gr .452 bullets in my 454 Casull, and am pushing them near max velocity.
I'm also using 200gr 10mm bullets going between 1100 and 1200 fps.
Remember that these are hard cast plated bullets and not softer lead plated.
I had contacted them directly for the load data I was considering for the 454 Casull and they said no problem.
My $0.02 anyways, take it for what it's worth.