I use it the arctic. Works great. I don't use it in high volume guns, I use Special Forces Dry lube then, with Otis regular on the really high friction areas.
A while ago I put several brands in little cups outside and Otis seized up the least, so that's what I use. It must have been -40 or so. All exhibited "freezing" traits to some degree. Windchill was higher as well, but I don't think that effected test as I had them in a protected porch.
Back to graphite... It doesn't seize, and it's used in door locks. The abrasives of it has to be minuscule, and unless you were planning on using it on "F" class... I wouldn't worry.
Some guns specify DO NOT USE though, like the XCR. I couldnt get an answer why.