That would be an unusual thing to do for maintenance.
It has been a long time since I worked on one but the barrel is screwed into the frame with a right hand thread. There may be a small pin through the frame that would require removal before trying the barrel. Of course you would remove the ejector housing first and the cylinder. Clamp the barrel in a vice using a barrel bushing that fits well and a wrench on the frame as close to the barrel as you can apply it.