I use the Hornady SST Interlocks in 25, 6.5mm, 7mm and 30 cal bullets on everything from coyotes, bears, deer to moose and elk.
They hold together well enough that I've never been able to recover a bullet because of full through penetration. The wound channel is around 2 inches in diameter.
So far I haven't been unlucky enough to have to take out a shoulder. Had the opportunity once last year but let the animal go instead. I hate ruining a quarter on any animal.
Those SSTs will perform exactly as they were designed to if you perform on your end.
Any bullet made, will cause meat to be bloodshot if you hit bone.
Some of the larger calibres, like the 338 and larger, with relatively heavy bullets won't damage as much meat but even then, a well placed shot to the boiler room is by far the best placement for any bullet. Mind you, there are always exceptions.