Pattern it at sixteen yards with a full or at least a tight choke... but you're not patterning for shot distribution/percentage, but rather the placement of the shot charge.
Put a fairly visible bullseye on a 3' x 3' square of paper. Get back exactly sixteen yards, and in one smooth motion, mount the gun quickly and touch it off just as you come up to the bull. This need be done fairly quickly and smoothly, without trying to consciously "aim" the shotgun, but rather just by quickly "pointing it" ... say as you would in a field situation with a flushing bird.
The exercise is to see " if the gun is shooting where you're looking" and not to see whether it shoots straight if you carefully "aim it" . About five of these "fit" patterns should tell, 10 are likely better. You are looking for a consistant or repetive trend in shot charge placement. If the shot charge is consistantly low, you need a higher comb, if the charge is always high - a lower comb. If the shot charge is to the left, you will need some cast-off
( if you're a right handed shooter) and if it's over to the right ( unusual) you may have to get some cast taken out, or the stock moved over to the left
( i.e., "cast-on") - Beware ... adding cast-on also seemingly has the compound effect of somewhat lowering the pattern. As I recall, every inch at 16 yards the pattern is out, translates to approximately 1/16" of change needed at the comb. To verify additional comb height being required, try taping on layers of thin cardboard ... say 1/16" at a time until you can see your shot pattern start moving up. If the shot charge is to high or to the left ( for righties ) , there's no much to do but start moving the stock around.
With the Beretta & Benelli auto-loaders, and a few others, the stock shims provided generally can give all the height of comb and cast-off required to fit most shooters. Most bumps & other auto loaders are fairly simple to move by a little judicious re-inletting. For good doubles & O/U's, leave the job to the pros ... either re-inletting or hot oil bending. Both are workable solutions that don't cost a huge amount, but really shouldn't be undertaken by amateurs.
IMHO .... in shotgunning ... " Fit & Balance" are everything. The gun has to shoot where you're looking !!!