Perhaps the best indicator is a falling off in the accuracy of the barrel. Target rifle shooters notice groups becoming vertical at long range; this results from increasing variation in muzzle velocity. If a barrel is well cleaned, you can observe throat erosion - right where the lands start - quite easily . This doesn't mean that the barrel is no longer shooting satisfactorily, but does indicate that there is significant wear. Some use borescopes, or plug gauges. Handloaders will notice that bullets must be seated further out to reach the rifling. Barrel life is dependent on the intensity of the round, to a great extent. A .308 barrel may be competitive for 5000+ rds, and give hunting acccuracy for 10 000 or more. A 6.5x.284 for 1500 or 2000. A .38 Special for untold thousands. Usually a barrel wears out at the throat first from a combination of erosion and heat; the passage of the bullet does not contribute much to wear. It is not uncommon for a barrel to be set back and rechambered to eliminate the eroded section. For many high intensity centrefire cartridges, the accurate lifespan of a barrel is 6 - 8 seconds. Take the number of milliseconds that it takes a bullet to pass through a barrel, multiply by some thousands, and the barrel's accurate lifespan can be measured in seconds. There have been military tests done to determine the number of rounds before the barrel will no longer stabilize a bullet, and it tumbles. This can take a very large number of rounds, although useful accuracy would have disappeared rather early on.