When you produce a handload, and the temperature is extremely cold, your velocity and pressure will be reduced. Therefore, more powder can be used and the load will be ok.If you use that same load in extremely hot temperatures, the pressure curve rises, velocity increases, and pressure can and will increase dramatically.If you stay within the guidelines of a good reloading manual,you should have no problems whatsoever. Bullet seating depth can cause pressures to skyrocket also.Seat your bullet so that it does not engage the lands when chambered. That way, it gets a little jump and some speed before it hits the rifling. If it is touching, the pressure has to rise very sharply to get it to move. All powders will give a variation if loaded and fired at 80 or 90 degrees, and then used at - 20 or -30. A hot - 30 degree load may be way too hot at 80 above. Hope that this helps. By the way, what are you loading for? Perhaps I can help.