The 'frangible' in frangible ammo has nothing to do with what it's made out of. Sort of. Frangible ammo bullets break up easily, but that doesn't mean lead free.
Don't think there's lead free .22 LR, haven't looked, but there are fully plated(tmj's etc) and fully jacketed(vs not. Military ball is not.) 9mm and .223. There are Barnes' copper bullets too.
Mind you, there is a lot of scary nonsense being promulgated about lead poisoning too. It takes a great deal of long term exposure. Shooting and reloading cast bullets does little unless you're casting in an unventilated or poorly ventilated room AND are exposed elsewhere. Like at work.
Anybody who does not wear a mask when shooting inside is nuts. But it's more about avoiding the black, um, crap you have to clean out of your snout than lead exposure.