My brother has had one for eons - like maybe 10 or 15 years. He has run some real warm loads through it, and it shoots pretty good. It do kick, however! I think he took a moose with it at around 40-50 yards. Hit it in the head, and the 350 grain softpoint blew the head up like a 22 hollowpoint on a partridge. He loves it, but he says you gotta hang on to it if you load it stiff.
He alos said, "If they didn't want you to put that much powder in the case, why on earth did they make the case so big?" He also has a contender barrel in 45-70, and THAT is a real experience you need to have.