While I certainly prefer CRF, I don't think that choice of action is the single factor by which a dangerous game rifle can be measured. If one word describes the dangerous game rifle it must be reliability. I rather doubt that the majority of .375's sold are ever tested against dangerous game, but that's besides the point. I believe these rifles must be built with that use in mind, and nothing short of absolute reliability is good enough.
When the action is worked, it will be worked with great force because the followup shot might have to be made very quickly. If the second round in the magazine jumps out as the bolt hits the stop, you are in serious trouble - regardless of which action you choose. I think that choosing the CRF is a good idea, but then you must take the extra step to ensure that the rifle works every time. Rounds cannot hang up in the magazine, nor jump out. It should not be difficult to lift the bolt handle when you work the action, yet there must be enough main spring energy to fire the cartridge every time. The trigger must be crisp and neither to light nor too heavy. The bolt cannot run across the top of the round without picking it up. When the round is picked up by the bolt, it must feed smoothly regardless of how blunt the bullet design. Ross Seyfried has written of rifles which will feed empty cases, and this is the kind of feeding that a DGR owner should strive for. The floor plate cannot swing open and dump your rounds in the dirt from the recoil of the first shot. The sights or cross hairs must immediately come into view without the shooter having to hunt for them. The double rifle I used when I went over seas was worth $40K, but to me it was worthless because when I threw it to my shoulder I had to wiggle it around to find the bead.
Mass production is responsible for the vast majority of the rifles we purchase. Some examples are very good, but unfortunately some are not so good. Expect some tweaking by a gunsmith to be required before your DGR's reliability becomes absolute.