In a bolt action 308, I would use 4895 speed powder for 150s and 4350ish powder for 180s.
For a semi I would use the faster powder (3031, H335, 748, 4895 RL15, Varget) for everything. This helps the gas system cope.
Like any other rifle, it will do better with some bullets than others. Personally, I like to develop a 180 gr load and use that for everything. If you have a buddy that loads, see if you can beg 10 180 gr bullets of several types/brands. This would save you buying a whole box and discovering the rifle does not like them.
Load 5 of each at the Start load for your powder, and the other 5 at +2 gr. Shoot these for groups, letting the rifle cool, and paying close attention to how close the first 3 group.
If any of these 180s groups at under 2" at 100 yards, you have a hunting load.