As most of you now know, I used to work in a ballistics R&D lab, and being a curious guy I tested a lot of my ideas and also had access to a lot of test results from other labs.
I ran a personal test (20 shots per flavour) of primer pocket conditioning and saw a very significant improvement by kissing the inside of the flash hole with a reamer, to take off the flash inside the case, made when the hole was punched. (Note: Not needed with Norma and Lapua brass). Other primer pocket conditioning either produced no benefit, or made things worse.
I have used a purpose made tool to do this and have also just used a 1/8" drill bit in an electric drill. If I have a bucket of brass to process, I lock the drill in a vice and that way I have two hands free to kiss the drill bit. As you touch the tool to the hole, you feel a bit of chatter as it hits the rough flash. As soon as it feels smooth, stop. Inside you should see a hole with a little champfer around it.
As for the flash hole, the bigger the hole the bigger the SD. So don't make the hole any bigger. SD is inversely proportional to hole size. That may be counter-intuitive - but don't argue with it. You may find some match brass has a smaller than usual flash hole that needs a small decapper pin. there is a reason for that small hole.