You may also want to try Trail Boss. I have not tried it in my 300 WM, but have used it in 22-250 (great 22 hornet simulator BTW), 7.62x39, 303 Brit and 308 win. I think it is a truly great powder. While it was originally intended for straight wall brass, it has proven effective in bottleneck cases as well. Look to be filling your cases from 70% - 90% capacity, before seating your bullet. I'd bet you could push a 180 around 1800-2000 fps for a nice, comfortable load.