With the 1:9 twist on the barrel, going with heavy & long bullets will probably work best. I don't see a point with going to limits on light or heavy end of the spectrum on most rifles (but I think fast twist - i.e. 1:9 - Lapua rifles prefer heavy). I'd rather find the most accurate load for a particular rifle in target & hunting and stick to it. It's better to go up or down in caliber (i.e. new rifle), instead of always changing bullet weights, which will affect accuracy - unless you don't care

Berger's Hybrids are less sensitive to seating depth than their VLDs BUT best accuracy usually comes from bullet seating just off or into the lands i.e. bullet ogive 0.010" into lands. If your loading to overall length (OAL) i.e. SAAMI/Factory spec, you won't get the true potential out of your rifle. You should be getting half MOA or better from the 110BA, if loads developed right, but keep in mind with heavy magnum, the bullets take longer distance before stabilized. Have fun
Might work good on your rifle:
110BA 1:9 Twist
TARGET
Hodgdon US869 powder (double benefit, this powder is also good for the 50cal)
Sierra 300gn MatchKing (SMK)
Berger 300gn Match Hybrid OTM Tactical
HUNTING
Barnes LRX 280gn [LRX all copper are awesome, accurate bullets!]
50
Hodgdon US869 or H50BMG powder
Try the 750gn Hornady AMAX
P.S. Generally speaking, throat erosion is what makes a 'barrel' wear out (groups open up). By seating bullets further out (after throat wears) you can keep the the accuracy of your barrel going for a while longer (this has limits too). Also, I only patch clean now (after seeing the Magpul shooting series) and even patching cleaning opens groups (meaning a few fouler shots to get tight again).