I think it depends what you want to use the rifle for. If it's a hunting/carry rifle, then I would go with a 2 piece lightweight setup, probably weaver or leupold rifleman rings and bases. If it's a big magnum and you have a big ass scope on it, you will need to go with steel rings and bases.
For a varmint or target rig, I like big, heavy, steel, 1 piece picatinny or weaver bases and steel rings. I use a Near 25moa base and steel TPS rings(no better rings for the price) on my Winchester Stealth. Farrel also makes nice bases and TPS now has a Rem700 base as well.
I have a leupold one piece base with those turn in rings on my savage, but I'm not real crazy about it. Doesn't give me confidence that it's as solid as weaver/picatinny setups.