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The differences between the 452 and 455 are so small it really comes down to which one is priced lower and which one has nicer walnut.
My 452 Varmint .22lr was a superb shooter (I completed the forum's rimfire challenge with it). Currently own a 455 Lux and it's a great rifle. I have never scoped it so I have yet to achive the accuracy of either of my old 452 Varmints, but it would probably be close with a scope.