I can vouch for 63.0g of H4350 with 180 TTSX.
LongBomber - What kind of velocities are you getting with that load (3082 fps is the listed max velocity for that bullet weight).
I've been keeping track of "pet loads" posted on various forums and here is a basic summary of what I've found: Overall, it seems the top 3 powders for 180's are H4350, IMR4350, and IMR4831 (H4831 also gets a notable # of recommendations)
H4350 - 64.0 g, 180 NosPT (60% posts using this bullet - 63.5 was the lowest, the 65.0 was the highest, but this was with 180 NosPT CT (I think it had lubalox or Moly coting and it is no longer made). That said 63.5-64.0 seems to be the most common H4350 load with this bullet wieght.
IMR4831 - 65.5 g, (75% posts with this combo180 NosAB)
IMR4350 - 50% of post using this powder listed 64.0 g - range was 63.5-64.5g (data for a variety of bullets - seems the sweet spot will fall in this narrow range).
There are a growing number of RL17 recommendations, but they are extremely variable (i.e., large range of charge recommendations). As such, I personally would wait until more published data appears (to my knowledge, only Speer Deepcurl and Alliant are the only ones who have published RL17 loads for 180 grains). The new Hornady 8 manual does not list this powder for the 300 WSM.
LongBomber touches on an important point - must of the pet loads I have come across lately are for 165/168 grain bullets - perhaps this is "the" bullet weight for the .300 WSM. If a mono-metal, 165s/168s will be adequate for any non-dangerous game in North America (according to John Barness).