300 wsm is not very fussy in my opinion.
My best powders are MagPro with scirrocos or Interbonds (150 and 165 gr)
H414/W760 with the same bullets adding Nosler 168 silvertips.
H4831sc has worked well with any bullet.
H4350 works as well as (or nearly so) H4831.
I don't have my books at hand, but any of the slower powders I listed have worked pretty well with most bullets I've tried. I'm guessing that with the bullet/powder combo's I have on hand, I've tried about 25 or 30 different ones. About 75% would be acceptable as hunting rounds (1-1/2" or under at 100 yds).
Lymans book on reloading has a nice mix of bullet/powder combos for the 300-and other wsm's.
I'm shooting out of a Savage (accutrigger) with a Wildcat Thumbhole, floated and bedded, 24" bbl, 4 - 20 Nikon scope.