I have owned at least one 225 Winchester for the past 20 years, and I really like the little semi-rim a lot.
[Keep in mind that I also own 222 Rems and 220 Swifts]
As has been said, It gives up very little to the 22-250, other than throat wear, which is noticeably less in the 225.
My present 225 is a custom gun....I used a take-off 40X barrel, and had it rechambered and fitted to a nice bolt action.
Even factory ammo is always sub-moa, and my handloads with the 50 or 55 Ballistic Tip and N140 often cluster around ½ moa.
Also working well in my 225 is W748, IMR 4895, IMR 4064 and Norma 202.
Quite versatile, and flat shooting, it is a very fine varmint cartridge.
Regards, Dave.