Use the powder maker's(Hodgdon) starting load and your issue will likely go away. Key holing is caused by undersized bullets, oversized barrels or too low velocity.
Hodgdon shows 40.0 as the starting load for a 65 grain bullet(just happens to be a V-Max). You do not need to reduce from there. Going too far under minimum can be as dangerous as going too far over max. Causes weird pressures.
Your OAL is to short too. Should be 2.600". You'll find your rifle likes heavier bullets better too. 85's and up. My .243, with the same twist, likes 90's and 105's with IMR4350.
Hornady's data is quite different than Hodgdon's. Doesn't mean their book is unsafe(also means desjardo's isn't either.)