Best is a matter of opinion, when people want different results it's impossible to pick one bullet that will make everyone happy. I like fast opening bullets for large wounds and couldn't care less about meat loss. The bigger the wound channel the better. A 150 grain Ballistic Tip is about as good as any, but realistically deer are neither big nor tough and aren't hard to kill with the most ordinary of bullets. They can be awfully hard to find though, and fast drops go a long ways to making it easier.